BRD4 ligand 6

Catalog No.: A40331
BRD4 Ligand
BRD4 ligand 6 is a selective BRD4 ligand that plays a crucial role in the development of BRD4-targeted PROTACs. It serves as a key building block for synthesizing PROTAC BRD4 Degrader-26, contributing to the advancement of research in targeted protein degradation and cancer therapies. This compound facilitates investigations into the inhibition of BRD4-related pathways, supporting studies focused on gene expression modulation and therapeutic interventions in oncological contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBRD4 ligand 6 is a selective BRD4 ligand that plays a crucial role in the development of BRD4-targeted PROTACs. It serves as a key building block for synthesizing PROTAC BRD4 Degrader-26, contributing to the advancement of research in targeted protein degradation and cancer therapies. This compound facilitates investigations into the inhibition of BRD4-related pathways, supporting studies focused on gene expression modulation and therapeutic interventions in oncological contexts.
Product Information
Catalog NumA40331
FormulaC22H25ClN6OS
Molecular Weight456.99
CAS Number1101702-80-0
SMILESNCCCNC(C[C@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1)=O
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