BRD8518

Name: BRD8518
Brand: Adooq Bioscience
SKU: A75867
Rating: 5 (288 reviews)

Catalog No.: A75867

PCSK9 Inhibitor

BRD8518 is a potent inhibitor of PCSK9, exhibiting an EC50 of 0.23 μM. By upregulating LDLR expression, BRD8518 effectively lowers blood lipid levels and enhances LDL uptake. This compound is valuable for research applications focused on cardiovascular diseases, facilitating the exploration of lipid metabolism and associated therapeutic strategies.

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Grouped product items
Size	Price	Stock
25mg	$3,250.00	In stock
50mg	$4,000.00	In stock
100mg	$5,200.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	BRD8518 is a potent inhibitor of PCSK9, exhibiting an EC50 of 0.23 μM. By upregulating LDLR expression, BRD8518 effectively lowers blood lipid levels and enhances LDL uptake. This compound is valuable for research applications focused on cardiovascular diseases, facilitating the exploration of lipid metabolism and associated therapeutic strategies.

Product Information

Catalog Num	A75867
Formula	C33H32F3N3O5
Molecular Weight	607.62
CAS Number	1565828-01-4
SMILES	O=C(NC1=CC=C2C(C(N(C)[C@H]3CC[C@@H](CC(NC4CC(C=CC=C5)=C5C4)=O)O[C@H]3CO2)=O)=C1)C6=CC=C(C(F)(F)F)C=C6

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