Brequinar

Catalog No.: A12442

Dihydroorotate Dehydrogenase Inhibitor

Brequinar

Brequinar Chemical Structure

CAS NO. 96187-53-0

Brequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$85.00
25 mg
$200.00
50 mg
$350.00
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Biological Activity

Brequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis.
In vitro DMSO 36 mg/mL (95.9 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.2 mL 266.4 mL
0.5 mM 5.33 mL 26.64 mL 53.28 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

*The above data is based on the productmolecular weight 375.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12442
Actions Inhibitor
CAS No. 96187-53-0
Formula C22H13F2NO2
M. Wt 375.37
Solubility DMSO
Purity >98%
SMILES CC1=C(N=C2C=CC(=CC2=C1C(=O)O)F)C3=CC=C(C=C3)C4=CC=CC=C4F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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