Fig. 1 · Structure

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Brigatinib A

GID4 Ligand

Brigatinib A is a ligand for GID4, serving a key role in targeted protein degradation strategies. This compound is utilized for the synthesis of PROTAC BCR-ABL Degrader-2, facilitating research on the modulation of protein levels in cancer cells. Its application in the development of innovative therapeutic approaches makes it an invaluable tool for cellular and molecular biology studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 1197958-90-9
Applications GID4 Ligand
Formula C23H28ClN6O2P
Molecular Weight 486.93
SMILES
COC1=CC(N2CCNCC2)=CC=C1NC3=NC=C(C(NC4=CC=CC=C4P(C)(C)=O)=N3)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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