Fig. 1 · Structure
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Brigatinib C
PROTAC Linker
Brigatinib C functions as a PROTAC linker, facilitating the targeted degradation of proteins through the ubiquitin-proteasome system. It plays a crucial role in the design of proteolysis-targeting chimeras (PROTACs), enhancing their ability to selectively eliminate disease-related proteins. This compound is essential for researchers studying targeted protein degradation and may contribute to the development of innovative therapeutic strategies in various disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1197958-75-0 |
| Applications | PROTAC Linker |
| Formula | C28H37ClN7O2P |
| Molecular Weight | 570.07 |
| SMILES | COC1=CC(N2CCC(CC2)N3CCNCC3)=CC=C1NC4=NC=C(C(NC5=CC=CC=C5P(C)(C)=O)=N4)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.