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Brigimadlin intermediate-1

Intermediate

Brigimadlin intermediate-1 is a key intermediate in the synthesis of Brigimadlin, an inhibitor of the E3 ubiquitin protein ligase MDM-2. This compound plays a crucial role in the development of Antibody-Drug Conjugates (ADCs), which are utilized in targeted cancer therapies. Its chemical properties facilitate the construction of novel therapeutic agents aimed at enhancing the efficacy of cancer treatments.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1149388-04-4
Applications	Intermediate
Formula	C₉H₁₀N₂O₄
Molecular Weight	210.19
SMILES	O=C(OC)C1=CC=C(N)C([N+]([O-])=O)=C1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.