Fig. 1 · Structure
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Brodimoprim
Dihydrofolate Reductase Inhibitor
Brodimoprim is a potent dihydrofolate reductase inhibitor with broad-spectrum antibacterial activity. As an orally active trimethoprim analogue, it exhibits significant efficacy against various gram-negative and gram-positive bacteria. This compound is valuable for research applications in studying bacterial resistance and the mechanisms of folate metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 56518-41-3 |
| Applications | Dihydrofolate Reductase Inhibitor |
| Formula | C13H15BrN4O2 |
| Molecular Weight | 339.19 |
| Synonyms | Ro 10-5970 |
| SMILES | COC1=C(C(OC)=CC(CC2=CN=C(N=C2N)N)=C1)Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.