Bromo-PEG3-azide is a PEG-based linker specifically designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its azide functional group enables efficient click chemistry applications, including copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-bearing molecules. Additionally, this compound can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified partners, facilitating the generation of multifunctional PROTACs for targeted protein degradation research.
Bromo-PEG3-azide is a PEG-based linker specifically designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its azide functional group enables efficient click chemistry applications, including copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-bearing molecules. Additionally, this compound can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified partners, facilitating the generation of multifunctional PROTACs for targeted protein degradation research.
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