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Bromo-PEG3-phosphonic acid diethyl ester

PROTAC Linker

Bromo-PEG3-phosphonic acid diethyl ester is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. Its structural features facilitate efficient conjugation to target proteins, enhancing the stability and efficacy of PROTAC molecules. This reagent is ideal for research applications focused on targeted protein degradation and the modulation of cellular signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1148026-98-5
Applications	PROTAC Linker
Formula	C₁₂H₂₆BrO₆P
Molecular Weight	377.21
SMILES	O=P(OCC)(CCOCCOCCOCCBr)OCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.