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Bromo-PEG4-NHS ester

PROTAC Linkers

Bromo-PEG4-NHS ester is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of target proteins to E3 ligase recruiting components, enhancing the efficacy of targeted protein degradation. Its versatile chemical properties make it suitable for various applications in chemical biology research, particularly in the development of novel therapeutics focusing on selective protein modulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2148295-98-9
Applications	PROTAC Linkers
Formula	C₁₅H₂₄BrNO₈
Molecular Weight	426.26
SMILES	O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCBr

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.