Bromoacetamido-PEG3-azide is a PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds. The versatility of Bromoacetamido-PEG3-azide makes it a valuable tool for chemical biology and therapeutic development.
Bromoacetamido-PEG3-azide is a PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds. The versatility of Bromoacetamido-PEG3-azide makes it a valuable tool for chemical biology and therapeutic development.
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