Bromoacetamido-PEG8-Boc

Catalog No.: A83951
PROTAC Linker
Bromoacetamido-PEG8-Boc is a polyethylene glycol (PEG)-based linker designed for use in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligase recruiters, promoting targeted protein degradation. It is particularly useful in chemical biology and drug discovery applications, where precise modulation of protein levels is required for studying cellular processes and therapeutic interventions.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBromoacetamido-PEG8-Boc is a polyethylene glycol (PEG)-based linker designed for use in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligase recruiters, promoting targeted protein degradation. It is particularly useful in chemical biology and drug discovery applications, where precise modulation of protein levels is required for studying cellular processes and therapeutic interventions.
Product Information
Catalog NumA83951
FormulaC25H48BrNO11
Molecular Weight618.55
CAS Number2055041-16-0
SMILESO=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CBr)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2