Fig. 1 · Structure

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Bromoacetamido-PEG8-Boc

PROTAC Linker

Bromoacetamido-PEG8-Boc is a polyethylene glycol (PEG)-based linker designed for use in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligase recruiters, promoting targeted protein degradation. It is particularly useful in chemical biology and drug discovery applications, where precise modulation of protein levels is required for studying cellular processes and therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2055041-16-0
Applications PROTAC Linker
Formula C25H48BrNO11
Molecular Weight 618.55
SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CBr)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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