Bromodomain inhibitor-13 is a selective inhibitor targeting bromodomain-containing proteins (BCPs), including SMARCA2, SMARCA4, and the bromodomain of PB1. It exhibits potent binding affinity with KD values of 37 nM for SMARCA2, 53 nM for SMARCA4, and 30 nM for PB1(5), alongside a KD of 190 nM for PB1(2). This compound is valuable for research into epigenetic regulation and the role of bromodomains in various cellular processes, making it a useful tool for studying gene expression modulation and protein interactions in cancer and other diseases.
Bromodomain inhibitor-13 is a selective inhibitor targeting bromodomain-containing proteins (BCPs), including SMARCA2, SMARCA4, and the bromodomain of PB1. It exhibits potent binding affinity with KD values of 37 nM for SMARCA2, 53 nM for SMARCA4, and 30 nM for PB1(5), alongside a KD of 190 nM for PB1(2). This compound is valuable for research into epigenetic regulation and the role of bromodomains in various cellular processes, making it a useful tool for studying gene expression modulation and protein interactions in cancer and other diseases.
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