BTI-322 is a human IgG1κ monoclonal antibody targeting the CD2 antigen expressed on T cells and natural killer (NK) cells. This reagent demonstrates potent immunosuppressive activity by effectively inhibiting T cell proliferation in response to alloantigens in vitro. BTI-322 is known to recognize a majority of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias, making it suitable for applications in research on renal allograft rejection and steroid-refractory acute graft-versus-host disease. Additionally, BTI-322 serves as a valuable tool for T-cell depletion studies in various immunological contexts.
BTI-322 is a human IgG1κ monoclonal antibody targeting the CD2 antigen expressed on T cells and natural killer (NK) cells. This reagent demonstrates potent immunosuppressive activity by effectively inhibiting T cell proliferation in response to alloantigens in vitro. BTI-322 is known to recognize a majority of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias, making it suitable for applications in research on renal allograft rejection and steroid-refractory acute graft-versus-host disease. Additionally, BTI-322 serves as a valuable tool for T-cell depletion studies in various immunological contexts.
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