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Retrocyclin-3

Catalog No.: A48748
Antimicrobial Peptide
Retrocyclin-3 is an antimicrobial peptide that targets viral infections, specifically human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV). It exhibits potent antiviral activity, making it a valuable tool for research into antiviral therapies and the mechanisms of viral resistance. Its unique structure and function offer insights into the development of novel antimicrobial strategies.
Retrocyclin-3 724760-21-8 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRetrocyclin-3 is an antimicrobial peptide that targets viral infections, specifically human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV). It exhibits potent antiviral activity, making it a valuable tool for research into antiviral therapies and the mechanisms of viral resistance. Its unique structure and function offer insights into the development of novel antimicrobial strategies.
Product Information
Catalog NumA48748
FormulaC82H146N36O18S6
Molecular Weight2116.66
CAS Number724760-21-8
SequenceCyclo(Arg-Arg-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Arg-Ile-Cys-Arg-Cys-Ile-Cys-Gly) (Disulfide bridge:Cys4-Cys17;Cys6-Cys15;Cys8-Cys13)
Sequence shorteningCyclo(RRICRCICGRRICRCICG) (Disulfide bridge:Cys4-Cys17;Cys6-Cys15;Cys8-Cys13)
SMILESO=C1[C@]2(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]3(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@](CSSC3)(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@](CSSC2)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@]4(CSSC[C@](NC(=O)[C@]([C@H](CC)C)(N1)[H])(C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)N4)[H])[H])[H])[H])[H])[H])[H])[H])[H]
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