Fig. 1 · Structure
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BU226 hydrochloride
Imidazoline 2 Receptors ligand
BU226 hydrochloride is a selective ligand for imidazoline 2 (I2) receptors, exhibiting a binding affinity with a Ki value of 1.4 nM for I2 receptors and an IC50 of 534.5 nM for I1 receptors. This compound plays a significant role in the investigation of antidepressant mechanisms. Its specificity makes it a valuable tool for research aimed at understanding the neurological effects and therapeutic potential of imidazoline receptor modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1186195-56-1 |
| Applications | Imidazoline 2 Receptors ligand |
| Formula | C12H12ClN3 |
| Molecular Weight | 233.70 |
| SMILES | C1(C2=NCCN2)=CC3=C(C=N1)C=CC=C3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.