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Buphanidrine

AChE Inhibitor

Buphanidrine is an acetylcholinesterase (AChE) inhibitor with an IC50 of 52.8 μM. This compound, isolated from Brunsvigia josephinae, demonstrates significant potential in the study of neurodegenerative diseases, particularly Alzheimer's disease. Its ability to modulate cholinergic signaling makes it a valuable tool for understanding the pathophysiology of cognitive decline and exploring therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1162-10-3
Applications	AChE Inhibitor
Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36
SMILES	COC1=C2C([C@]34[C@](C[C@H](C=C4)OC)([H])[N@](C2)CC3)=CC5=C1OCO5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.