Fig. 1 · Structure
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BUR1
Cat. No.
A84903
CAS
23000-46-6
BMP Upregulator
BUR1 is a bone morphogenetic protein (BMP) upregulator that primarily activates BMPRII signaling with an EC50 of 98 nM. It effectively induces the expression of BMP2 and PTGS2, making it a valuable tool in studies related to BMP signaling pathways. Additionally, BUR1 has been shown to reverse pulmonary arterial pressure in monocrotaline-induced rat models, highlighting its potential applications in cardiovascular and pulmonary research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23000-46-6 |
| Applications | BMP Upregulator |
| Formula | C16H17N5 |
| Molecular Weight | 279.34 |
| SMILES | C12=NC=NC(N3CCCCC3)=C1C=NN2C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.