Fig. 1 · Structure
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Butaprost
EP2 Agonist
Butaprost is a selective agonist for the prostaglandin E receptor subtype EP2, exhibiting an EC50 of 33 nM and a Ki of 2.4 μM for the murine EP2 receptor. It demonstrates minimal activity against murine EP1, EP3, and EP4 receptors. This compound effectively attenuates fibrosis by inhibiting TGF-β/Smad2 signaling pathways, making it a valuable tool for research in fibrosis and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 69685-22-9 |
| Applications | EP2 Agonist |
| Formula | C24H40O5 |
| Molecular Weight | 408.57 |
| SMILES | COC(CCCCCC[C@@H](C(C[C@H]1O)=O)[C@H]1/C=C/C[C@@H](C2(CCC2)CCC)O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.