Fig. 1 · Structure

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Butyne-DOTA-tris(t-butyl ester)

BFC

Butyne-DOTA-tris(t-butyl ester) is a bifunctional chelator (BFC) and a macrocyclic DOTA derivative designed for tumor pre-targeting applications. This reagent facilitates the conjugation of peptides and radionuclides, enhancing the efficacy of targeted therapy in cancer research. Its structural properties make it suitable for developing imaging agents and therapeutic compounds in biomedical studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2125661-54-1
Applications BFC
Formula C32H57N5O7
Molecular Weight 623.82
SMILES
O=C(CN1CCN(CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(NCCC#C)=O)CC(OC(C)(C)C)=O)OC(C)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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