Fig. 1 · Structure

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Butyne-DOTA

BFC

Butyne-DOTA is a bifunctional chelator (BFC) and a macrocyclic derivative of DOTA, designed for enhanced tumor pre-targeting applications. This compound facilitates the conjugation of peptides and radionuclides, making it a valuable tool in the development of targeted radiotherapy strategies. Its ability to form stable complexes with metal ions is essential for advancing research in molecular imaging and therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2125661-62-1
Applications BFC
Formula C20H33N5O7
Molecular Weight 455.51
SMILES
O=C(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(NCCC#C)=O)CC(O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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