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Buxbodine B

Catalog No.: A78851
AChE Inhibitor
Buxbodine B is an acetylcholinesterase (AChE) inhibitor with an IC50 of 50 μM. It demonstrates significant potential in the study of neurodegenerative diseases, particularly Alzheimer's disease, by modulating cholinergic transmission. Its inhibitory action on AChE facilitates the exploration of therapeutic strategies aimed at enhancing cognitive function and memory retention in affected populations.
Buxbodine B 390362-51-3 AChE Inhibitor
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Size Price Stock Qty
5mg
$515.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBuxbodine B is an acetylcholinesterase (AChE) inhibitor with an IC50 of 50 μM. It demonstrates significant potential in the study of neurodegenerative diseases, particularly Alzheimer's disease, by modulating cholinergic transmission. Its inhibitory action on AChE facilitates the exploration of therapeutic strategies aimed at enhancing cognitive function and memory retention in affected populations.
Product Information
Catalog NumA78851
FormulaC26H41NO2
Molecular Weight399.61
CAS Number390362-51-3
SMILESC[C@]12[C@@]3([H])[C@@]4(CC[C@@]1([C@@]([C@H](C2)O)([H])[C@H](C)N(C)C)C)[C@@]5([C@@](C(C)(C(C=C5)=O)C)([H])CC3)C4
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Neuronal Signaling > AChE