BVT173187 is a selective inhibitor of the CXCR target, effectively blocking the activation of the neutrophil formyl peptide receptor FPR1. This compound suppresses FPR1 agonist-induced activation in neutrophils, leading to decreased mobilization of adhesion molecules and reduced superoxide anion production. In addition to its strong effects on FPR1, BVT173187 also influences C5aR and CXCR signaling pathways, making it a valuable tool for research in inflammation and immune response.
BVT173187 is a selective inhibitor of the CXCR target, effectively blocking the activation of the neutrophil formyl peptide receptor FPR1. This compound suppresses FPR1 agonist-induced activation in neutrophils, leading to decreased mobilization of adhesion molecules and reduced superoxide anion production. In addition to its strong effects on FPR1, BVT173187 also influences C5aR and CXCR signaling pathways, making it a valuable tool for research in inflammation and immune response.
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