Bz-VGR-AMC

Catalog No.: A77358
Substrate For The Trypsin-like Activity Of 20S Proteasome
Bz-VGR-AMC is a synthetic substrate specifically designed for the trypsin-like activity of the 20S proteasome. This compound enables the quantification of β2 activity within the proteasome, serving as a valuable tool for researching proteasomal function and regulation. Its application is particularly relevant in studies investigating cellular protein degradation, signaling pathways, and disease mechanisms associated with proteasomal dysregulation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBz-VGR-AMC is a synthetic substrate specifically designed for the trypsin-like activity of the 20S proteasome. This compound enables the quantification of β2 activity within the proteasome, serving as a valuable tool for researching proteasomal function and regulation. Its application is particularly relevant in studies investigating cellular protein degradation, signaling pathways, and disease mechanisms associated with proteasomal dysregulation.
Product Information
Catalog NumA77358
FormulaC30H37N7O6
Molecular Weight591.66
CAS Number87779-49-5
Sequence{Bz}-Val-Gly-Arg-{AMC}
Sequence shortening{Bz}-VGR-{AMC}
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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