Fig. 1 · Structure
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C2 Adamantanyl globotriaosylceramide (d18:1/2:0)
Globotriaosylceramide Analog
C2 Adamantanyl globotriaosylceramide (d18:1/2:0) is a water-soluble analog of globotriaosylceramide that acts as a bioactive sphingolipid. This compound effectively reverses multidrug resistance in MDR1-expressing MDCK cells, facilitating enhanced drug uptake and efficacy. Additionally, it exhibits a high affinity for verotoxin (VT), making it a valuable tool for research into sphingolipid-related cellular responses and mechanisms of drug resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 261155-87-7 |
| Applications | Globotriaosylceramide Analog |
| Formula | C48H83NO18 |
| Molecular Weight | 962.17 |
| Synonyms | AdaGb3; Adamantyl Gb3; C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0) |
| SMILES | OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)CO)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CC45CC6CC(CC(C6)C5)C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.