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Biological Activity
C527 is a is a pan DUB enzyme inhibitor, with a high potency for the USP1/UAF1 complex (IC50=0.88 μM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.1 mL | 170.5 mL | 341.01 mL |
| 0.5 mM | 6.82 mL | 34.1 mL | 68.2 mL |
| 1 mM | 3.41 mL | 17.05 mL | 34.1 mL |
| 5 mM | 0.68 mL | 3.41 mL | 6.82 mL |
*The above data is based on the productmolecular weight 293.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21365 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 192718-06-2 |
| Formula | C17H8FNO3 |
| M. Wt | 293.25 |
| Purity | >98% |
| Synonyms | C-527; C 527 |
| SMILES | O=C1C2=C(N=C(C3=CC=C(F)C=C3)O2)C(C4=CC=CC=C41)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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