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PI3K inhibitor

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Catalog No. A15030

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CAL-130 5mg A15030-5
CAL-130 10mg A15030-10
CAL-130 50mg A15030-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that combined inhibition of PI3K??/?? as therapy for T cell acute lymphoblastic leukemia (T-ALL).


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Chemical Information

Catalog Num A15030
Actions Inhibitor
M. Wt 426.47
Formula C23H22N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1431697-74-3
Synonyms CAL130, CAL 130
SMILES code CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)C(C)NC4=NC(=NC5=C4NC=N5)N
Chemical Name 2-[(1S)-1-[(2-amino-7H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one

Biological Activity

CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that combined inhibition of PI3K??/?? as therapy for T cell acute lymphoblastic leukemia (T-ALL).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.45 mL 117.24 mL 234.48mL
0.5 mM 4.69 mL 23.45 mL 46.9 mL
1 mM 2.34 mL 11.72 mL 23.45 mL
5 mM 0.47 mL 2.34 mL 4.69 mL

*The above data is based on the productmolecular weight 426.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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