Calcineurin Autoinhibitory Peptide

Catalog No.: A15376

Calcineurin Autoinhibitory Peptide

Calcineurin Autoinhibitory Peptide Chemical Structure

CAS NO. 148067-21-4

Calcineurin inhibitory peptide is a selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 uM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).

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1 mg
$160.00
5 mg
$480.00
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Biological Activity

Calcineurin inhibitory peptide is a selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 uM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 3.41 mL 17.06 mL 34.12 mL
0.5 mM 0.68 mL 3.41 mL 6.82 mL
1 mM 0.34 mL 1.71 mL 3.41 mL
5 mM 0.07 mL 0.34 mL 0.68 mL

*The above data is based on the productmolecular weight 2930.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15376
CAS No. 148067-21-4
Formula C124H205N39O39S
M. Wt 2930.7
Purity >98%
SMILES CC[[email protected]](C)[[email protected]@H](C(=O)N[[email protected]@H]([[email protected]@H](C)O)C(=O)N[[email protected]@H](CO)C(=O)N[[email protected]@H](CC1=CC=CC=C1)C(=O)N[[email protected]@H](CCC(=O)O)C(=O)N[[email protected]@H](CCC(=O)O)C(=O)N[[email protected]@H](C)C(=O)N[[email protected]@H](CCCCN)C(=O)NCC(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](CC(=O)O)C(=O)N[[email protected]@H](CCCNC(=N)N)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N[[email protected]@H](CC(=O)N)C(=O)N[[email protected]@H](CCC(=O)O)C(=O)N[[email protected]@H](CCCNC(=N)N)C(=O)N[[email protected]@H](CCSC)C(=O)N2CCC[[email protected]]2C(=O)N3CCC[[email protected]]3C(=O)N[[email protected]@H](CCCNC(=N)N)C(=O)N[[email protected]@H](CCCNC(=N)N)C(=O)N[[email protected]@H](CC(=O)O)C(=O)N[[email protected]@H](C)C(=O)N[[email protected]@H](CCSC)C(=O)N4CCC[[email protected]]4C(=O)O)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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