Canertinib dihydrochloride

Catalog No.: A11344

EGFR inhibitor

Canertinib dihydrochloride

Canertinib dihydrochloride Chemical Structure

CAS NO. 289499-45-2

Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM.

Availability: In stock

Package Price Qty
50 mg
$72.00
100 mg
$124.00
500 mg
$368.00
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Biological Activity

Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.89 mL 89.47 mL 178.94 mL
0.5 mM 3.58 mL 17.89 mL 35.79 mL
1 mM 1.79 mL 8.95 mL 17.89 mL
5 mM 0.36 mL 1.79 mL 3.58 mL

*The above data is based on the productmolecular weight 558.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11344
Actions Inhibitor
M. Wt 558.86
Formula C24H27Cl3FN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 289499-45-2
Synonyms CI-1033 dihydrochloride; PD-183805 dihydrochloride
SMILES C=CC(NC1=CC2=C(N=CN=C2C=C1OCCCN3CCOCC3)NC4=CC=C(C(Cl)=C4)F)=O.[H]Cl.[H]Cl

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