Cannflavin B is a natural flavonoid isolated from Cannabis sativa L. with a primary mechanism as an inhibitor of PGE2 release, mPGES-1, and 5-lipoxygenase. This compound exhibits a range of biological activities, including anti-inflammatory, antioxidant, anti-glycation, anti-ferroptosis, anti-tumor, and anti-Leishmania effects, with an IC50 of 14 μM for Leishmania. Additionally, Cannflavin B has been shown to inhibit the TrkB-BDNF signaling pathway, making it a valuable tool for research in inflammation and cancer biology.
Cannflavin B is a natural flavonoid isolated from Cannabis sativa L. with a primary mechanism as an inhibitor of PGE2 release, mPGES-1, and 5-lipoxygenase. This compound exhibits a range of biological activities, including anti-inflammatory, antioxidant, anti-glycation, anti-ferroptosis, anti-tumor, and anti-Leishmania effects, with an IC50 of 14 μM for Leishmania. Additionally, Cannflavin B has been shown to inhibit the TrkB-BDNF signaling pathway, making it a valuable tool for research in inflammation and cancer biology.
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