Fig. 1 · Structure
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Canocapavir
Antiviral Agent
Canocapavir is an orally active antiviral agent targeting the hepatitis B virus (HBV) core protein. By binding to the hydrophobic pocket at the dimer-dimer interface of HBV core protein (HBc), it stimulates the intracellular accumulation of nonfunctional HBV capsids, thereby disrupting viral replication. Additionally, Canocapavir inhibits the interaction between HBc and the HBV large surface protein, leading to a reduction in the production of empty virions. This compound is valuable for research into HBV infection and its therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2137847-19-7 |
| Applications | Antiviral Agent |
| Formula | C27H21BrFN5O3 |
| Molecular Weight | 562.39 |
| Synonyms | ZM-H1505R |
| SMILES | O=C1NC2=CC=C(C=C2N1)CCN3[C@@](OCC3=O)([H])C4=CN(C5=CC=C(C=C5)Br)N=C4C6=CC=C(C=C6)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.