Fig. 1 · Structure
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Canosimibe
Cholesterol Absorption Inhibitor
Canosimibe is a cholesterol absorption inhibitor that selectively targets and modulates intestinal cholesterol uptake. This compound has demonstrated the ability to reduce cholesterol levels, making it a valuable reagent in studies focused on lipid metabolism and cardiovascular health. Canosimibe is utilized in research applications related to hyperlipidemia and the exploration of therapeutic strategies for atherosclerosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 768394-99-6 |
| Applications | Cholesterol Absorption Inhibitor |
| Formula | C44H60FN3O10 |
| Molecular Weight | 809.96 |
| Synonyms | AVE-5530; BART-1741 |
| SMILES | O[C@H](C1=CC=C(C=C1)F)CC[C@@H]2[C@](C3=CC=C(C=C3)OC)([H])N(C4=CC=C(C=C4)CNC(CCCCCCCCCCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)C2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.