Fig. 1 · Structure

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Cap-dependent endonuclease-IN-12

Cap-dependent Endonuclease Inhibitor

Cap-dependent endonuclease-IN-12 is a selective inhibitor of cap-dependent endonuclease targeting viral RNA synthesis. It demonstrates significant inhibitory activity against the H1N1 virus while exhibiting low cytotoxicity. This reagent is primarily utilized in antiviral research and studies investigating the mechanisms of RNA virus replication.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2460686-97-7
Applications Cap-dependent Endonuclease Inhibitor
Formula C55H46F4N6O14S2
Molecular Weight 1155.11
SMILES
O=C1N(CCOC2)[C@]2([H])N([C@H]3C4=CC=C(F)C(F)=C4CSC5=CC=CC=C53)N(C=CC6=O)C1=C6OCOC(OCCCOC(OCOC7=C8N(C=CC7=O)N([C@H]9C%10=CC=C(F)C(F)=C%10CSC%11=CC=CC=C%119)[C@@]%12([H])N(CCOC%12)C8=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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