Capeserod hydrochloride is a potent partial agonist of the 5-HT4(e) receptor, demonstrating a Ki value of 0.6 nM. This compound effectively stimulates cAMP production in cells expressing both 5-HT4(b) and 5-HT4(e) splice variants, with IC50 values of 244 nM and 29 nM, respectively. Capeserod hydrochloride is primarily utilized in research focused on cognitive enhancement, memory impairment, and dementia-related studies.
Capeserod hydrochloride is a potent partial agonist of the 5-HT4(e) receptor, demonstrating a Ki value of 0.6 nM. This compound effectively stimulates cAMP production in cells expressing both 5-HT4(b) and 5-HT4(e) splice variants, with IC50 values of 244 nM and 29 nM, respectively. Capeserod hydrochloride is primarily utilized in research focused on cognitive enhancement, memory impairment, and dementia-related studies.
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