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Caplacizumab
Caplacizumab (ALX-0681) is a humanized nanobody targeting the von Willebrand factor (vWF), designed to disrupt the interaction between vWF and platelet glycoprotein Ibα. By inhibiting this binding, Caplacizumab effectively prevents vWF-mediated platelet adhesion, thereby reducing the formation of microthrombi. This agent is particularly useful for research focused on thrombotic thrombocytopenic purpura (TTP), offering a valuable tool for investigating the mechanisms and potential treatments of this condition.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 915810-67-2 |
| Molecular Weight | 27876 |
| Synonyms | ALX-0681; ALX-0081 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.