CatB-IN-1 is a potent inhibitor of serine/threonine proteases, specifically targeting cathepsin B. This compound exhibits significant anti-invasive activity in various cellular models, effectively reducing the invasiveness of tumor cells such as MCF-10A neoT. Research indicates that CatB-IN-1 can modulate intracellular protein metabolism, thereby influencing tumor cell behavior. Its structure-activity relationship highlights its capability to engage multiple functions of cathepsin B, making it a valuable tool for studies on tumor invasion and metastasis.
CatB-IN-1 is a potent inhibitor of serine/threonine proteases, specifically targeting cathepsin B. This compound exhibits significant anti-invasive activity in various cellular models, effectively reducing the invasiveness of tumor cells such as MCF-10A neoT. Research indicates that CatB-IN-1 can modulate intracellular protein metabolism, thereby influencing tumor cell behavior. Its structure-activity relationship highlights its capability to engage multiple functions of cathepsin B, making it a valuable tool for studies on tumor invasion and metastasis.
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