(+)-Catechin 3-gallate

Catalog No.: A77363
Proteasome Inhibitor
(+)-Catechin 3-gallate is a polyphenolic compound that functions as a non-selective proteasome inhibitor. It demonstrates antitumor activity by inducing apoptosis and decreasing the levels of inflammatory cytokines. This agent is of significant interest in cancer research, particularly for breast and prostate cancers, as well as in the study of neurodegenerative diseases such as Alzheimer's.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(+)-Catechin 3-gallate is a polyphenolic compound that functions as a non-selective proteasome inhibitor. It demonstrates antitumor activity by inducing apoptosis and decreasing the levels of inflammatory cytokines. This agent is of significant interest in cancer research, particularly for breast and prostate cancers, as well as in the study of neurodegenerative diseases such as Alzheimer's.
Product Information
Catalog NumA77363
FormulaC22H18O10
Molecular Weight442.37
CAS Number25615-05-8
SMILESO=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@@H](C3=CC(O)=C(C=C3)O)OC4=CC(O)=CC(O)=C4C2
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