Fig. 1 · Structure
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CAY10499
Lipase Inhibitor
CAY10499 is a non-selective lipase inhibitor that targets monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) with IC50 values of 144 nM and 14 nM, respectively. This compound demonstrates significant anti-inflammatory and antiviral properties, making it suitable for research applications in studying lipid metabolism, inflammation, and viral infections. Its dual inhibition profile offers potential insights into therapeutic interventions for related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 359714-55-9 |
| Applications | Lipase Inhibitor |
| Formula | C18H17N3O5 |
| Molecular Weight | 355.34 |
| Synonyms | MAGL-IN-5 |
| SMILES | O=C(OCC1=CC=CC=C1)NC2=CC=C(N3C(OC(OC)=N3)=O)C=C2C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.