CAY10669 is a PCAF inhibitor that functions through the inhibition of histone acetyltransferase activity. With an IC50 value of 662 μM, CAY10669 enhances SAHA-induced acetylation in HEPG2 cells and promotes transgene expression in CHO-K1 cells. Additionally, it demonstrates cytotoxic effects in zebrafish embryos, making it a valuable tool for studying histone modification and gene expression regulation in various biological contexts.
CAY10669 is a PCAF inhibitor that functions through the inhibition of histone acetyltransferase activity. With an IC50 value of 662 μM, CAY10669 enhances SAHA-induced acetylation in HEPG2 cells and promotes transgene expression in CHO-K1 cells. Additionally, it demonstrates cytotoxic effects in zebrafish embryos, making it a valuable tool for studying histone modification and gene expression regulation in various biological contexts.
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