Fig. 1 · Structure
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CB-5339
p97 Inhibitor
CB-5339 is a potent inhibitor of p97, exhibiting an IC50 of less than 30 nM. This compound has demonstrated significant biological activity, making it a valuable tool for investigating the role of p97 in various cellular processes. Its use in leukemia research provides insights into potential therapeutic strategies and mechanisms underlying the disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1863952-15-1 |
| Applications | p97 Inhibitor |
| Formula | C24H24N6O |
| Molecular Weight | 412.49 |
| SMILES | O=C(C1=CC=CC2=C1C=C(C)N2C3=NC(NCC4=CC=CC=C4)=C(CCCN5)C5=N3)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.