Fig. 1 · Structure
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CB30900
Thymidylate Synthase Inhibitor
CB30900 is a selective inhibitor of thymidylate synthase, demonstrating an IC50 of 0.2 μM. This compound exhibits significant cytotoxicity in the W1L2 cell line, with an IC50 value of 0.13 μM. It is valuable for research applications focusing on cancer biology and the mechanisms of nucleotide metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 145788-82-5 |
| Applications | Thymidylate Synthase Inhibitor |
| Formula | C31H32FN5O9 |
| Molecular Weight | 637.61 |
| SMILES | O=C1C2=CC(CN(C3=CC(F)=C(C=C3)C(N[C@H](C(O)=O)CCC(N[C@@H](C(O)=O)CCC(O)=O)=O)=O)CC#C)=C(C)C=C2NC(C)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.