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CBR 5884

PHGDH inhibitor

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Catalog No. A16176

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CBR 5884 5mg A16176-5
€47.50
CBR 5884 10mg A16176-10
€85.50
CBR 5884 50mg A16176-50
€342.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM.

CBR 5884

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Chemical Information

Catalog Num A16176
Actions Inhibitor
M. Wt 336.38
Formula C14H12N2O4S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 681159-27-3
Synonyms CBR-5884, CBR5884
SMILES CCOC(=O)C1=C(C(=C(S1)NC(=O)C2=CC=CO2)SC#N)C

Biological Activity

Description
CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.73 mL 148.64 mL 297.28mL
0.5 mM 5.95 mL 29.73 mL 59.46 mL
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL

*The above data is based on the productmolecular weight 336.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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