cBu-Cit-OH

Catalog No.: A43273
ADC Linker
cBu-Cit-OH is a cyclic alkene-based linker designed for antibody-drug conjugate (ADC) applications. This reagent facilitates the stable attachment of cytotoxic agents to antibodies, enhancing targeted delivery and efficacy in cancer therapeutics. Its unique structural properties enable effective conjugation, making it suitable for the synthesis and development of innovative ADCs in research settings.
Grouped product items
Size Price Stock Qty
25mg
$1,350.00
In stock
50mg
$1,765.00
In stock
100mg
$2,135.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptioncBu-Cit-OH is a cyclic alkene-based linker designed for antibody-drug conjugate (ADC) applications. This reagent facilitates the stable attachment of cytotoxic agents to antibodies, enhancing targeted delivery and efficacy in cancer therapeutics. Its unique structural properties enable effective conjugation, making it suitable for the synthesis and development of innovative ADCs in research settings.
Product Information
Catalog NumA43273
FormulaC28H38N6O7
Molecular Weight570.64
CAS Number1799663-03-8
SMILESOCC1=CC=C(NC([C@H](CCCNC(N)=O)NC(C2(C(NCCCCCN3C(C=CC3=O)=O)=O)CCC2)=O)=O)C=C1
SynonymsMal-cyclobutane-1,1-dicarboxamide-Cit-PAB
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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