Fig. 1 · Structure

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Cbz-aminooxy-PEG8-acid

PROTAC Linkers

Cbz-aminooxy-PEG8-acid is a PEG-based PROTAC linker designed for the development of proteolysis-targeting chimeras (PROTACs). This compound features an aminooxy group that facilitates the covalent attachment of target proteins, enhancing selective degradation. Its application in drug discovery and chemical biology makes it an essential tool for researchers focused on targeted protein modulation and therapeutic development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2353410-09-8
Applications PROTAC Linkers
Formula C27H45NO13
Molecular Weight 591.65
SMILES
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCONC(OCC1=CC=CC=C1)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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