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Cbz-PEG5-Br

PROTAC Linkers

Cbz-PEG5-Br is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Its structure facilitates the conjugation of target ligands to E3 ligase recruiters, enhancing the development of bifunctional compounds that promote targeted protein degradation. This reagent is essential for researchers focusing on the modulation of protein levels in various biological pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2710803-69-1
Applications	PROTAC Linkers
Formula	C₂₀H₃₂BrNO₇
Molecular Weight	478.37
SMILES	O=C(NCCOCCOCCOCCOCCOCCBr)OCC1=CC=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.