Fig. 1 · Structure

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CCI17464

EP4 Agonist

CCI17464 is a selective, orally active EP4 partial agonist with a pKi of 7.1. This compound demonstrates significant biological activity in the modulation of inflammatory responses and has been effectively utilized in the Freund's complete adjuvant (FCA) acute rat inflammatory pain model. CCI17464 shows promise in the complete reversal of allergic reactions, making it a valuable tool for research in inflammation and allergic responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Partial Agonist
CAS Number 325780-75-4
Applications EP4 Agonist
Formula C24H23NO5
Molecular Weight 405.44
SMILES
O=C(CC1=CC=C(N2C(C3=C(C4=C(C(OCC)=C3C2)C=CC=C4)OCC)=O)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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