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Biological Activity
CCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 6.22 mL | 31.1 mL | 62.2 mL |
| 0.5 mM | 1.24 mL | 6.22 mL | 12.44 mL |
| 1 mM | 0.62 mL | 3.11 mL | 6.22 mL |
| 5 mM | 0.12 mL | 0.62 mL | 1.24 mL |
*The above data is based on the productmolecular weight 1607.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18411 |
|---|---|
| CAS No. | 1452145-13-9 |
| Formula | C72H110N12O27S |
| M. Wt | 1607.77 |
| Purity | >98% |
| SMILES | CC(C)(C)C(CN1C2=CC=CC=C2N(C3CCCCC3)C[C@@H](NC(NC4=CC(C(NCCCCCCCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=CC=C4)=O)C1=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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