CD12681 is a selective inverse agonist of RORγ, exhibiting IC50 values of 19 nM and 10 nM against RORγ GAL4 and CD4-IL-17 cells, respectively. This compound effectively reduces IL-17-mediated inflammatory cell recruitment, making it a valuable tool for studying inflammatory pathways. CD12681 shows promise for research applications in conditions such as psoriasis, facilitating the exploration of novel therapeutic strategies.
CD12681 is a selective inverse agonist of RORγ, exhibiting IC50 values of 19 nM and 10 nM against RORγ GAL4 and CD4-IL-17 cells, respectively. This compound effectively reduces IL-17-mediated inflammatory cell recruitment, making it a valuable tool for studying inflammatory pathways. CD12681 shows promise for research applications in conditions such as psoriasis, facilitating the exploration of novel therapeutic strategies.
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