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CDD-1115

BMPR2 Inhibitor

CDD-1115 is a selective inhibitor of Bone Morphogenetic Protein Receptor Type 2 (BMPR2) with an IC50 of 1.8 nM and an apparent Ki of 6.2 nM. This compound inhibits BMP-mediated gene expression, which plays a critical role in various cellular processes across diverse tissues, including the kidney, skeletal muscle, heart, and reproductive organs. CDD-1115 is ideal for investigating the regulatory effects of BMP signaling and its involvement in ectopic bone formation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034215-86-3
Applications	BMPR2 Inhibitor
Formula	C₃₂H₃₀N₆O₃
Molecular Weight	546.62
SMILES	NC(C1=CC=CC(CNC(C2=CC=C3N=C(C4=CC5=C(C=NC=C5)C=C4)N([C@H]6C[C@@H](CC6)C(NC)=O)C3=C2)=O)=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.