CDD-1349

Catalog No.: A40427
BRDT-BD2/BRD4-BD2 Inhibitor
CDD-1349 is a selective inhibitor of the BRDT-BD2 and BRD4-BD2 bromodomains, demonstrating a sixfold selectivity for BRDT-BD2 over BRD4-BD2. With an IC50 value of 22 nM against BRDT, this compound serves as a valuable tool in the exploration of nonhormonal contraceptive agents. Its targeted activity makes it suitable for research focused on reproductive biology and potential contraceptive development.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCDD-1349 is a selective inhibitor of the BRDT-BD2 and BRD4-BD2 bromodomains, demonstrating a sixfold selectivity for BRDT-BD2 over BRD4-BD2. With an IC50 value of 22 nM against BRDT, this compound serves as a valuable tool in the exploration of nonhormonal contraceptive agents. Its targeted activity makes it suitable for research focused on reproductive biology and potential contraceptive development.
Product Information
Catalog NumA40427
FormulaC31H29N7O3
Molecular Weight547.61
CAS Number2757619-90-0
SMILESO=C(C1=CC=C(C(NC)=O)C=C1)NC2=CC(NC(C3=CC(C(C4=C(C)C=C(N)N=C4)=NN5C)=C5C=C3)=O)=CC=C2C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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